.hero[data-astro-cid-dnmgl4w7]{background:linear-gradient(135deg,#1a4d2e,#0d2818);color:#fff;padding:4rem 2rem;text-align:center}.hero[data-astro-cid-dnmgl4w7] h1[data-astro-cid-dnmgl4w7]{font-size:2.5rem;margin-bottom:1rem;color:gold}.lead[data-astro-cid-dnmgl4w7]{font-size:1.25rem;line-height:1.8;max-width:800px;margin:0 auto 2rem}.badges[data-astro-cid-dnmgl4w7]{display:flex;gap:1rem;justify-content:center;flex-wrap:wrap}.badge[data-astro-cid-dnmgl4w7]{background:#fff3;color:#fff;padding:.5rem 1rem;border-radius:4px;font-size:.875rem;font-weight:600}.safety-overview[data-astro-cid-dnmgl4w7],.side-effects[data-astro-cid-dnmgl4w7],.contraindications[data-astro-cid-dnmgl4w7],.interactions[data-astro-cid-dnmgl4w7],.overdose[data-astro-cid-dnmgl4w7],.safety-studies[data-astro-cid-dnmgl4w7],.recommendations[data-astro-cid-dnmgl4w7]{padding:4rem 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#ff980040}.toxicology-card[data-astro-cid-dnmgl4w7] h3[data-astro-cid-dnmgl4w7]{color:#e65100;margin-bottom:1.25rem;font-size:1.3rem;border-bottom:2px solid #ffb74d;padding-bottom:.5rem}.toxicology-card[data-astro-cid-dnmgl4w7] p[data-astro-cid-dnmgl4w7]{line-height:1.8;margin-bottom:1rem}.toxicology-card[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7]{list-style:none;padding:0;margin:1rem 0}.toxicology-card[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]{padding-left:2rem;position:relative;margin-bottom:.75rem;line-height:1.7}.toxicology-card[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]:before{content:"▸";position:absolute;left:0;color:#ff9800;font-size:1.2rem;font-weight:700}.toxicology-conclusion[data-astro-cid-dnmgl4w7]{background:#ff980026;border-radius:6px;padding:1rem;margin-top:1.5rem;font-weight:600;color:#e65100}.special-populations[data-astro-cid-dnmgl4w7]{padding:4rem 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th[data-astro-cid-dnmgl4w7]{background:#1a4d2e;color:#fff;padding:1.25rem;text-align:left;font-weight:600}.monitoring-table[data-astro-cid-dnmgl4w7] td[data-astro-cid-dnmgl4w7]{padding:1rem 1.25rem;border-bottom:1px solid #e0e0e0}.monitoring-table[data-astro-cid-dnmgl4w7] tr[data-astro-cid-dnmgl4w7]:last-child td[data-astro-cid-dnmgl4w7]{border-bottom:none}.monitoring-table[data-astro-cid-dnmgl4w7] tr[data-astro-cid-dnmgl4w7]:nth-child(2n){background:#f8f9fa}.monitoring-notes[data-astro-cid-dnmgl4w7]{background:#ffd7001a;border:2px solid #ffd700;border-radius:8px;padding:2rem}.monitoring-notes[data-astro-cid-dnmgl4w7] h3[data-astro-cid-dnmgl4w7]{color:#1a4d2e;margin-bottom:1.5rem}.monitoring-notes[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7]{list-style:none;padding:0}.monitoring-notes[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]{padding-left:2rem;position:relative;margin-bottom:.75rem}.monitoring-notes[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]:before{content:"ℹ️";position:absolute;left:0;font-size:1.2rem}.decision-tree[data-astro-cid-dnmgl4w7]{padding:4rem 2rem;background:linear-gradient(135deg,#e3f2fd,#bbdefb)}.decision-tree[data-astro-cid-dnmgl4w7] h2[data-astro-cid-dnmgl4w7]{color:#1a4d2e;text-align:center;margin-bottom:1rem;font-size:2rem}.decision-tree[data-astro-cid-dnmgl4w7] .section-intro[data-astro-cid-dnmgl4w7]{text-align:center;max-width:900px;margin:0 auto 3rem;color:#555;font-size:1.1rem}.decision-flowchart[data-astro-cid-dnmgl4w7]{max-width:1200px;margin:0 auto}.decision-node[data-astro-cid-dnmgl4w7]{background:#fff;border:3px solid #1976d2;border-radius:12px;padding:2rem;text-align:center;margin-bottom:3rem;box-shadow:0 8px 20px #1976d233}.decision-node[data-astro-cid-dnmgl4w7] h3[data-astro-cid-dnmgl4w7]{color:#1976d2;margin-bottom:1rem;font-size:1.5rem}.decision-grid[data-astro-cid-dnmgl4w7]{display:grid;grid-template-columns:repeat(auto-fit,minmax(300px,1fr));gap:2rem}.decision-card[data-astro-cid-dnmgl4w7]{background:#fff;border-radius:12px;padding:2rem;box-shadow:0 6px 16px #0000001f}.decision-card[data-astro-cid-dnmgl4w7].contraindicated{border:4px solid #f44336;background:#f443360d}.decision-card[data-astro-cid-dnmgl4w7].contraindicated h4[data-astro-cid-dnmgl4w7]{color:#f44336;margin-bottom:1.5rem;font-size:1.3rem}.decision-card[data-astro-cid-dnmgl4w7].caution{border:4px solid #ff9800;background:#ff98000d}.decision-card[data-astro-cid-dnmgl4w7].caution h4[data-astro-cid-dnmgl4w7]{color:#ff9800;margin-bottom:1.5rem;font-size:1.3rem}.decision-card[data-astro-cid-dnmgl4w7].safe{border:4px solid #4caf50;background:#4caf500d}.decision-card[data-astro-cid-dnmgl4w7].safe h4[data-astro-cid-dnmgl4w7]{color:#4caf50;margin-bottom:1.5rem;font-size:1.3rem}.decision-card[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7]{list-style:none;padding:0}.decision-card[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]{padding-left:1.5rem;position:relative;margin-bottom:.75rem;line-height:1.7;text-align:left}.decision-card[data-astro-cid-dnmgl4w7].contraindicated ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]:before{content:"✗";position:absolute;left:0;color:#f44336;font-weight:700;font-size:1.2rem}.decision-card[data-astro-cid-dnmgl4w7].caution ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]:before{content:"⚠";position:absolute;left:0;font-size:1.1rem}.decision-card[data-astro-cid-dnmgl4w7].safe ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]:before{content:"✓";position:absolute;left:0;color:#4caf50;font-weight:700;font-size:1.2rem}.start-tip[data-astro-cid-dnmgl4w7]{background:#4caf5026;padding:1rem;border-radius:6px;margin-top:1.5rem;text-align:left}.longterm-safety[data-astro-cid-dnmgl4w7]{padding:4rem 2rem;background:#fff}.longterm-safety[data-astro-cid-dnmgl4w7] h2[data-astro-cid-dnmgl4w7]{color:#1a4d2e;text-align:center;margin-bottom:1rem;font-size:2rem}.longterm-safety[data-astro-cid-dnmgl4w7] .section-intro[data-astro-cid-dnmgl4w7]{text-align:center;max-width:900px;margin:0 auto 3rem;color:#555;font-size:1.1rem}.longterm-grid[data-astro-cid-dnmgl4w7]{display:grid;gap:2.5rem}.longterm-card[data-astro-cid-dnmgl4w7]{background:linear-gradient(135deg,#f8f9fa,#e9ecef);border:3px solid #2e7d4e;border-radius:12px;padding:2.5rem;box-shadow:0 8px 20px #2e7d4e26}.longterm-card[data-astro-cid-dnmgl4w7] h3[data-astro-cid-dnmgl4w7]{color:#1a4d2e;margin-bottom:1.25rem;font-size:1.5rem;border-bottom:2px solid #ffd700;padding-bottom:.75rem}.longterm-card[data-astro-cid-dnmgl4w7] p[data-astro-cid-dnmgl4w7]{line-height:1.8;margin-bottom:1.5rem}.longterm-card[data-astro-cid-dnmgl4w7] h4[data-astro-cid-dnmgl4w7]{color:#2e7d4e;margin-top:1.5rem;margin-bottom:1rem}.longterm-card[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7]{list-style:none;padding:0}.longterm-card[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]{padding-left:2rem;position:relative;margin-bottom:.75rem;line-height:1.7}.longterm-card[data-astro-cid-dnmgl4w7] ul[data-astro-cid-dnmgl4w7] li[data-astro-cid-dnmgl4w7]:before{content:"✓";position:absolute;left:0;color:#2e7d4e;font-weight:700;font-size:1.2rem}.longterm-note[data-astro-cid-dnmgl4w7]{background:#2196f31f;border-left:4px solid #2196f3;padding:1.25rem;margin-top:1.5rem;font-size:.95rem}@media(max-width:768px){.hero[data-astro-cid-dnmgl4w7] h1[data-astro-cid-dnmgl4w7]{font-size:2rem}.side-effects-grid[data-astro-cid-dnmgl4w7],.interaction-grid[data-astro-cid-dnmgl4w7],.recommendation-grid[data-astro-cid-dnmgl4w7],.overdose-info[data-astro-cid-dnmgl4w7],.ae-stats[data-astro-cid-dnmgl4w7],.toxicology-grid[data-astro-cid-dnmgl4w7],.population-grid[data-astro-cid-dnmgl4w7],.decision-grid[data-astro-cid-dnmgl4w7]{grid-template-columns:1fr}.monitoring-table[data-astro-cid-dnmgl4w7]{font-size:.85rem}.monitoring-table[data-astro-cid-dnmgl4w7] th[data-astro-cid-dnmgl4w7],.monitoring-table[data-astro-cid-dnmgl4w7] td[data-astro-cid-dnmgl4w7]{padding:.75rem}}